Here's everything you need to know about the Facebook CEO's wife…
Who is Priscilla Chan?
Priscilla Chan, 33, is an American philanthropist and paediatrician and she's married to Mark Zuckerberg.
Priscilla's parents were Chinese refugees who fled Vietnam in boats, she grew up speaking both Cantonese and English.
Priscilla was born and raised in Massachusetts.
In 2003 Priscilla graduated as class valedictorian, the highest ranking student among her peers, and she was voted "class genius" by her fellow students.
Priscilla then attended Harvard University where she met and began dating Mark Zuckerberg, the founder and CEO of Facebook.
After graduating with a BA in biology in 2007 Priscilla continued her education and in 2015 she finished her paediatric residency.
How many children do the couple have?
On July 31, 2015, Zuckerberg announced that he and Chan were expecting a baby girl.
He said he felt confident that the risk of miscarrying was low so far into the pregnancy, after Chan had already suffered three miscarriages.
Their first child, Maxima Chan Zuckerberg or “Max”, was born on November 30, 2015.
On August 28, 2017, they announced the birth of their second child called August.
The pair posted a picture of their family on Facebook, of course, with a message to their new daughter.
It read in part: "August, we love you so much and we're so excited to go on this adventure with you. We wish you a life of joy, love and the same hope you give us."
When did Priscilla Chan marry Mark Zuckerberg?
After meeting Mark while at university in 2003, the couple dated for nine years before they decided to tie the knot in 2012.
The pair have two children together.
Their wedding took place in the garden of their California mansion.
Those who attended the wedding told the New York Times the dinner menu included sushi and Mexican food while Billie Joe Armstrong from Green Day performed.
What is the Chan Zuckerberg Initiative and the Biohub?
Launched in December 2015, the Chan Zuckerberg Initiative is a philanthropic organisation.
According to its website, its aim is to bring together "world-class engineering, grant-making, impact investing, policy, and advocacy work".
The Chan Zuckerberg Initiative focuses on supporting science through biomedical research and personalised learning.
In September 2016, the Initiative committed to contribute $600million over the next decade to the CZ Biohub, a non-profit organisation in San Francisco, which brings together physicians, scientists and engineers.
The Biohub's aim to bring together Bay-area researchers and scientists from the University of California at San Francisco, the University of California at Berkeley and Stanford University.
Although they work closely together, the Chan Zuckerberg Initiative and CZ Biohub are separate organisations, operating independently.
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