The extraordinary blunder came to light after a 26-year-old man and his 24-year-old wife went to see an obstetrician about their lack of success.
When Dr Liu Hongmei investigated further she found out the woman had regular sex but that it was "unusually painful" every time.
At first Dr Lui thought her patient might be suffering some sort of disease or disorder.
But according to China’s Guiyang Evening Post, further examinations found the clueless couple from Bijie city in China’s south-western Guizhou province, had been having anal sex all along.
Further tests confirmed this and amazingly found the wife was virgin.
Dr Lui said: "Four years of marriage and neither the husband nor wife knew how to get pregnant.
“Couples so lacking in general knowledge are very rare.
"But it is not uncommon for people to lack or have misconceptions regarding sexual knowledge."
The doctor then reportedly handed the couple each a sex-ed handbook and also gave them "guidelines" before they were sent home.
The advice appeared to work, as news of the wife’s pregnancy arrived just a few months later.
They reportedly informed the doctor that they were finally expecting – and sent 100 eggs and a live hen as gifts.
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