With Juventus falling to a shock defeat to Young Boys, the Red Devils could finish first with a victory over their Spanish opponents and now face an arguably more difficult test in the next round.
Who can Manchester United face in last 16?
United's second place finish means they will face a harder draw in the next round of the Champions League.
They will have to face one of the group winners – but will avoid Cristiano Ronaldo's Juventus.
The Red Devils can face:
- Borussia Dortmund
- Barcelona
- Paris Saint-Germain
- Porto
- Bayern Munich
- Real Madrid
When is the Champions League draw?
The draw will take place on Monday, December 17.
It will begin at 11am UK time.
It is being held at Uefa's headquarters in Nyon, Switzerland.
When are the remaining Champions League matches?
12/13 and 19/20 February: Round of 16 first leg
5/6 and 12/13 March: Round of 16 second leg
15 March: Quarter-final and semi-final draw
9/10 April: Quarter-finals first leg
16/17 April: Quarter-finals second leg
30 April/1 May: Semi-finals first leg
7/8 May: Semi-finals second leg
1 June: Final (Estadio Metropolitano, Madrid)
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