The Home Nations are competing for the Doddie Weir Cup, which has been commissioned in support of the former Scotland and Lions star who has been diagnosed with Motor Neurone Disease.
Warren Gatland's men ran out 34-7 winners when Wales met Scotland in the Six Nations earlier this year.
What time is kick-off?
THIS autumn Test is all set for Saturday, November 3.
Kick-off at the Principality Stadium is at 2.45pm.
Which TV channel is Wales vs Scotland on and can I live stream it?
YOU can find this one live on BBC ONE from 2.15pm.
That means you can also stream via the BBC iPlayer, which will give you the option to watch from the beginning.
In Wales, the game will be broadcast along with Welsh commentary on S4C.
How do I watch Wales vs Scotland for free?
BBC One and the BBC iPlayer are free for all UK residents with a TV licence.
A TV licence costs £150.50 for colour and £50.50 for black and white.
Over 75s are entitled to a free TV licence.
What is the team news?
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