Gareth Southgate's men were beaten by La Roja at Wembley last month and must win this time out to have a chance of making the Uefa Nations League final four.
When does Spain vs England kick-off?
This UEFA Nations League fixture takes place on Monday October 15.
It will kick-off at 7:45 pm UK time.
The game is being played at Estadio Benito Villamarin in Seville.
What TV channel is Spain vs England on and can I live stream it?
The game will be shown live on Sky Sports Main Event.
Sky subscribers will be able to get this online and on the Sky Sports Mobile app.
Or if you're not a Sky subscriber, you can watch all the action live with a NOW TV Sports Pass from £7.99.
What are the latest odds?
Bookies and fans alike have written off England’s inexperienced team for a famous victory in Spain tonight, according to betting intelligence site bookmakers.tv.
England’s win odds have drifted from 3/1 to 5/1 as punters pile into Spain, who are hot 8/13 favourites for victory, commanding a huge 68% of bets. The stalemate is 3/1 with another bore draw an outside chance at 10/1.
But those who think hotshot youngster Jadon Sancho can save the day against Spain will get odds of 16/1 about him scoring the winning goal while it's 6/1 he finds the back of the net at any time.
What is the team news for Spain vs England?
England
Spain
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