Already trailing the Italians by five points, Jose Mourinho's side would love to get one over Cristiano Ronaldo and Co on their own patch.
Juve have won all three of their group games so far and are yet to concede a goal in this year's competition.
But history is on the Red Devils' side, with their last visit here a 3-0 victory way back in 2003.
What time is kick-off?
THIS Champions League tie is set for Wednesday, November 7.
Kick-off is at 8pm.
The match will be held at the Allianz Stadium.
Paulo Dybala was the match-winner when the sides met two weeks ago, firing the winner at Old Trafford in a 1-0 win.
Which TV channel can I watch it on?
YOU can watch this game play out live on BT Sport 2.
Coverage starts at 7.45pm and you can also live stream using the BT Sport app on your mobile, tablet or Windows 10 device.
As usual we will be running a comprehensive LIVE BLOG here on SunSport if you're unable to watch.
What is the team news?
Full team news to follow.
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