Ernesto Valverde's side have won the competition on 30 occasions, with the last being a crushing 5-0 win over Sevilla last season.
What time does Cultural Leonesa vs Barcelona kick off?
Cultural Leonesa host Barcelona TONIGHT.
Kick-off in the first leg at the Reino de Leon is at 8:30pm. The second leg is not scheduled until 5 December.
The Catalans have won their last four games in all competitions, a run which includes the recent 5-1 El Clasico thrashing of Real Madrid.
Leonesa have won five of their last six games and have gone through three rounds to reach this stage, beating Navalcarnero, Fuenlabrada and Lorca FC en route to the last-32.
Which TV channel is Cultural Leonesa vs Barcelona on and can I live stream it?
Cultural Leonesa vs Barcelona is not available to watch live on TV in the UK but is being broadcast online by Bet365.
Additionally, you can follow all the action as it happens via the SunSport LIVE blog.
What is the team news?
The hosts are unlikely to make many changes for the first leg against Barcelona, with the game representing one of the biggest in the careers of many of their players.
Forward Aridane is expected to lead the line and represents perhaps the biggest threat to Barca, having netted seven goals this season.
Valverde is likely to rest a number of his first choice stars following El Clasico. Youth players Lana Cerevic, Inaki Pena, Chumi, Jorge Cuenca, Juan Miranda and Riqui Puig could all be involved after training with the first team this week.
Barcelona are definitely without three players due to injury however, with Lionel Messi, Samuel Umtiti and Thomas Vermaelen all out.
Source: Read Full Article