Sex hormone oestrogen makes women enjoy cannabis more, study finds

Sex hormone oestrogen makes women enjoy cannabis more than men, study finds

  • Women enjoy the cannabis high more than men because of oestrogen hormone
  • Women also have a higher chance of cannabis addiction than men, study finds
  • Study says men are FOUR times more likely to try cannabis and in higher doses

Women are more likely to become addicted to cannabis because the sex hormone oestrogen makes them enjoy the high more, a study has found.

Men are up to four times more likely to try cannabis and use higher doses, more frequently, due to their levels of testosterone, the review of studies into animal behaviour revealed.

Despite females using the drug less, they went from first hit to habit faster than males. 

Men are up to four times more likely to try cannabis and use higher doses, more frequently, researchers revealed [File photo]

This is due to being more sensitive to the drug’s effects and the release of the ‘pleasure’ and ‘reward’ brain chemicals. 

The differences between how cannabis affects the sexes is important as more countries look to decriminalise or legalise cannabis. 

This month, Canada became the second country to legalise the drug for recreational use.

The findings could lead to gender-based drug addiction treatments. The differences between how cannabis affects the sexes is important as more countries look to decriminalise or legalise cannabis [File photo]

The research found the differences in response were down to the influence of sex hormones like testosterone, oestradiol (oestrogen) and progesterone on the endocannabinoid system.

This is a network of brain cells which communicate using the same family of chemicals found in cannabis. 

Study co-author Dr Liana Fattore, of the National Research Council of Italy, said: ‘Male sex steroids increase risk-taking behaviour and suppress the brain’s reward system, which could explain why males are more likely to try drugs, including cannabis.’

The research found the differences in response were down to the influence of sex hormones like testosterone [File photo]

She added: ‘Females seem to be more vulnerable, at a neurochemical level, in developing addiction to cannabis.’

The findings could lead to gender-based drug addiction treatments. 

Professor Fattore told the journal Frontiers in Behavioural Neuroscience: ‘Identifying factors is critical for optimising evidence-based prevention and treatment protocols.’

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