Gilead buys Forty Seven for $4.9B to bolster cancer drug pipeline

FILE – This July 9, 2015, file photo shows the headquarters of Gilead Sciences in Foster City, Calif. (AP Photo/Eric Risberg, File)

(Reuters) - Gilead Sciences Inc said on Monday it would buy Forty Seven Inc for $4.9 billion in cash, adding an experimental treatment that targets blood cancer to its portfolio of oncology drugs.

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Shares of Forty Seven jumped 62 percent, trading slightly below the offer price of $95.50 per share. Gilead shares were up 2.3 percent at $70.95 in early morning trading.

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The deal is expected to compliment the portfolio of Kite Pharma Inc, which the company acquired for $12 billion in 2017, and comes at a time when sales of Gilead's hepatitis C drugs have seen a steep fall.

"The deal is in line with the strategy CEO Daniel O'Day had laid out earlier in the year, but I think he and his management need to do something more impactful," Credit Suisse analyst Evan Seigerman told Reuters.

Ticker Security Last Change Change %
GILD GILEAD SCIENCES INC. 74.21 -1.19 -1.58%
FTSV FORTY SEVEN INC 94.24 +0.33 +0.35%

Through the acquisition, Gilead will have access to Forty Seven's lead drug, magrolimab, which switches off a "do not eat me" signal known as CD47 expressed by tumor cells that lets them avoid destruction. The drug is in early-stage testing.

CD47 antibodies are a relatively new class of drugs in development for treating cancer, a lucrative but difficult market to enter for drugmakers.

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Initially focused on treating blood cancers called myelodysplastic syndromes, magrolimab could be used alongside Yescarta, a CAR-T therapy Gilead gained through the Kite acquisition, in the future, Gilead executives said.

"There are studies ongoing and data being generated in DLBCL, and that's one of those areas where I think you could imagine that there could be … possibilities," Gilead Chief Medical Officer Merdad Parsey said.

Diffuse large B-cell lymphoma, or DLBCL, is a type of non-Hodgkin's lymphoma that is currently being treated with Yescarta and for which magrolimab is being tested as a treatment.

Gilead's Yescarta, a CAR-T therapy added through the acquisition of Kite, has gained market share as a treatment for certain types of DLBCL, SunTrust analysts said on Thursday, citing a Bloomberg News report that Gilead had approached Forty Seven with a takeover offer.

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However, the market could in the future be split between treatments such as Forty Seven's magrolimab and CAR-T therapies, according to SunTrust analysts Robyn Karnauskas and Asthika Goonewardene.

(Reporting by Manas Mishra and Trisha Roy in Bengaluru; Editing by Saumyadeb Chakrabarty and Anil D'Silva)

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