The Chilean forward, 29, missed training this morning along with five other first-team stars who will miss Champions League game.
Marouane Fellani, Phil Jones, Scott McTominay, Jesse Lingard and Diogo Dalot were all missing from this morning's session.
And ahead of tomorrow's night's crucial Group H game, Mourinho said: “The players you saw are the ones who are available.
"Nothing to hide. Alexis is out.”
That means the SIX stars missing from today's training are officially out of contention – including Sanchez.
In Sanchez's absence, Anthony Martial is expected to take on a leading role, fresh from his two-goal heroics from the 2-2 draw with Chelsea.
Asked whether Martial's goals had helped their relationship, Mourinho said: "Come on – things were not tense between us to begin with.
“We have a player-coach relationship and I hope that we will continue like that and bring Manchester United as much as possible."
United will play Juventus in the third Champions League group stage game tomorrow night at Old Trafford.
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