The Brazilian striker has been dropped to the bench for the match despite seeing fellow attackers Sadio Mane and Mo Salah line up on the wings.
Jurgen Klopp has instead opted to go with Daniel Sturridge in Serbia as his Reds look to come home with all three points.
Firmino was in stunning form for Liverpool last season as they lost to Real Madrid in the Champions League final while securing a top four Premier League finish.
The ace scored 27 goals in all competitions, but it was his link play which allowed Salah to go on his incredible 44-goal run.
However, Firmino is finding good form hard to come by this term, scoring just four times in 15 appearances.
And Klopp appears to feel that a fresher Sturridge is the better option for tonight, with the England hopeful already impressing with a number of fine appearances off the bench.
Joel Matip is back in the heart of defence alongside Virgil van Dijk.
While Adam Lallana is given a chance in midfield as he looks to fight his way back into Klopp’s plans.
Divock Origi could also be set for his first appearance of the season after making the bench ahead of Xherdan Shaqiri, who has been left at home for political reasons.
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