The Cottagers full-back, 20, had to be replaced by Cyrus Christie after just five minutes of the game following the awful injury.
Fosu-Mensah was down for around three minutes in real pain after landing awkwardly on his arm early in the Fulham's game with Everton.
The on-loan Manchester United defender had attempted to challenge Calvert-Lewin – but fell to the ground in sickening manner.
Fosu-Mensah was stretchered off and carried down the tunnel clutching his arm in serious discomfort.
The Dutch ace could now be out for as much as four months with the injury, depending on the severity in a huge blow for both player and club.
The game was poised at 0-0 at the time, with both clubs aiming to break out of the bottom ten.
While the Fosu-Mensah update looks bad, there has been some good news for Fulham fans recently.
The club officially opened talks with Ryan Sessegnon regarding a new contract.
Sessegnon, 18, is regarded as one of England's brightest young talents and is already attracting the interest of big clubs in the Premier League and abroad.
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