The Notorious tapped out in the fourth round of his lightweight world title fight as Russian Nurmagomedov did all his talking in the ring.
Jericho was asked on Twitter whether he would consider "UFC as the next stop"?
Despite McGregor's name not even mentioned in the original question posed by Aakash Srivastava, the wrestling legend answered: "Why not! I could probably beat @TheNotoriousMMA at this point…"
Reigning champ Nurmagomedov secured a rear-naked choke in the fourth round to secure victory.
And it has emerged the Russian, 30, was in a dominant position after taking the first two rounds – the second 10-8 – before McGregor won the third.
The Irish fighter could not handle his unbeaten rival, who retained his UFC lightweight title.
The match will be most remembered for the ugly scenes afterwards as Khabib launched himself at the Irishman's team after jumping out of the Octagon.
McGregor meanwhile was also involved in a scrap as his opponent's entourage confronted him.
UFC president Dana White confirmed: "Khabib jumped over the cage to go after one of Conor’s guys who was talking trash about him.
"I don’t know what to say. I’m just disgusted. [Conor is] OK. He’s upset about the fight but not about that.
"The guys who jumped in will never fight here again.
"I've been working hard to promote this sport, this is not what a mixed martial arts event is normally like."
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