Here's everything you need to know about the night from the hosts to the schedule.
When is Stand Up To Cancer 2018 on TV?
Stand Up To Cancer 2018 will take off with a live show on Friday, October 26 on Channel 4.
Specific times are still to be announced, but in previous years the show had started at 8 pm.
the show is set to be full of star-studded sketches, emotional moments and famous sketches.
Channel 4’s Head of Entertainment Ed Havard said: “Stand Up To Cancer has grown into the most ambitious TV event on Channel 4, raising many millions of pounds to fund groundbreaking cancer trials.
"We are hugely grateful to all the stars involved in this campaign, and of course to the public who have donated so generously."
Who's hosting the night?
The night will be hosted by three famous television personalities.
One of these is Maya Jama who has just been on our screens as the host of The Circle.
The Australian comedian and broadcast presenter Adam Hills from The Last Leg will be joining her.
And lastly, the legendary TV personality and comedian Alan Carr will be one of the hosts.
What's the schedule on the night?
The schedule for the night hasn't been revealed just yet.
However, we do know that previous year's schedules have been jampacked with laughter, emotion and fun.
We also know that there will be quite a few special shows as a part of Stand Up To Cancer.
These include Celebrity Gogglebox, Celebs First Dates, Celebrity Haunted and Celebrity Call Centre.
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