Manuel Pellegrini's side have already taken points off Manchester United and Chelsea this season and will be looking to put a dent in the Gunners top-three challenge.
What time is kick-off?
THIS Premier League clash is set for Saturday, February 12.
Kick-off at the London Stadium is at 12.30pm.
When the sides met earlier in the season, the Gunners ran out 3-1 winners at the Emirates.
Which TV channel can I watch it on?
YOU can watch this one live on Sky Sports Premier League, Main Event and Ultra HD.
Coverage begins at midday, whilst non-Sky subscribers can still watch by purchasing a NOW TV pass from just £7.99.
Here at SunSport we'll be running a LIVE BLOG from East London which will bring you all the goals and talking points as they happen.
What is the team news?
Arsenal's injury problems are not looking any better, after Laurent Koscielny was injured before their FA Cup win against Blackpool.
He joins Hector Bellerin, Nacho Monreal, Mesut Ozil, Shkodran Mustafi and Henrikh Mkhitaryan on the sidelines.
But the Gunners could see the return of young Greek defender Konstantinos Mavropanos after he returned to training.
West Ham also have an injury crisis on their hands, with Fabian Balbuena, Javier Hernandez and Marko Arnautovic among them.
Andriy Yarmolenko, Jack Wilshere, Manuel Lanzini, Ryan Fredericks and Winston Reid are all expected to return at some stage this season – but Carlos Sanchez will not play until the 2019/20 campaign.
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