The Toon have won only one of their last nine games in all competitions.
They visit Chelsea on Saturday sitting just two points above the Premier League drop zone.
And Perez is massively concerned by Newcastle’s form, especially at home where they have won just twice all the season.
The Spaniard, 25, said: “Something is wrong. I don't know what exactly but it is a strange thing.
“We keep struggling at St James’ Park and we can't struggle as much as we are in home games – that means something is wrong.
"It is strange because there is no consistency. Sometimes it is individual performances, sometimes it's not like that and it's team performance.
"It can't be individual every time as we have changed players and rotated.
“I think there is a piece of the jigsaw that is missing.It is holding us back and it's why we are struggling.
“We've won twice at home and that's just not acceptable. It's not good enough so something should change.
“It's going to be a long January but we must stick together and face up to it."
In contrast to their St James’ Park problems, Newcastle have only lost three league games on their travels – and they have been at Manchester City, Manchester United and Liverpool.
Perez added: “Away from home we have been better which is the strange thing. That is one positive.
"But imagine if we were better at home? We wouldn't be in trouble now.
"We should be looking forward to playing Chelsea with the pressure off – it should be enjoyable.
"Chelsea will be tough but we have done well away so hopefully we can get a result.”
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